Sesquiterpene Glucosides from Chloranthus japonicusSieb.

Abstract A new lindenane sesquiterpene glucoside named yinxiancaoside A ( 1 ), a new, rare bidesmosidic megastigmane sesquiterpene glucoside named yinxiancaoside B ( 5 ), and three known sesquiterpene glucosides, chloranoside A ( 2 ), pisumionoside ( 3 ), and sarcaglaboside A ( 4 ), were isolated from the whole plant of Chloranthus japonicus Sieb . The structures of the new compounds were established by an extensive study of their spectral data, especially 1D‐ and 2D‐NMR. The cytotoxic activity of the isolated compounds against human hepatoma (Hepg‐2), human ovarian carcinoma (OV420), and human breast cancer (MCF‐7) cells was investigated.