过氧化氢
化学
水溶液
抗坏血酸
激进的
试剂
无机化学
催化作用
羟基自由基
芬顿试剂
氧化剂
过氧化物
氯化物
氧气
有机化学
芬顿反应
食品科学
作者
Justin N. Cross,Robert P. Currier,Dennis Torraco,Laura A. Vanderberg,Gregory L. Wagner,P. D. Gladen
标识
DOI:10.1128/aem.69.4.2245-2252.2003
摘要
ABSTRACT An approach to decontamination of biological endospores is discussed. Specifically, the performance of an aqueous modified Fenton reagent is examined. A modified Fenton reagent formulation of cupric chloride, ascorbic acid, and sodium chloride is shown to be an effective sporicide under aerobic conditions. The traditional Fenton reaction involves the conversion of hydrogen peroxide to hydroxyl radical by aqueous ionic catalysts such as the transition metal ions. Our modified Fenton reaction involves the conversion of aqueous dissolved oxygen to hydrogen peroxide by an ionic catalyst (Cu 2+ ) and then subsequent conversion to hydroxyl radicals. Results are given for the modified Fenton reagent deactivating spores of Bacillus globigii . A biocidal mechanism is proposed that is consistent with our experimental results and independently derived information found in the literature. This mechanism requires diffusion of relatively benign species into the interior of the spore, where dissolved O 2 is then converted through a series of reactions which ultimately produce hydroxyl radicals that perform the killing action.
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