Do 1-year outcomes predict 2-year outcomes for adult deformity surgery?

医学 外科 脊柱畸形 队列 回顾性队列研究 畸形 最小临床重要差异 Oswestry残疾指数
作者
Steven D. Glassman,Frank J. Schwab,Keith H. Bridwell,Christopher I. Shaffrey,William C. Horton,Serena S. Hu
出处
期刊:The Spine Journal [Elsevier BV]
卷期号:9 (4): 317-322 被引量:41
标识
DOI:10.1016/j.spinee.2008.06.450
摘要

Abstract Background Context Health-related quality-of-life (HRQOL) measures are being used more frequently in the evaluation of the adult deformity patient. This is due in part to the validation of the deformity-specific Scolios Research Society-22 (SRS-22). Hence, relationships between HRQOL outcomes and traditional measures of success such as deformity correction, fusion healing, and complications are being established. Purpose To examine the pattern of HRQOL outcome responses after adult deformity surgery. Study design Analysis of prospective multicenter cohort. Patient sample Two hundred and eighty-three adult deformity patients with preoperative, 1-, and 2-year postoperative outcome measures. Outcome measures SRS-22, Short Form-12 (SF-12), Oswestry Disability Index (ODI), and back and leg pain numeric rating scale scores. Methods Preoperative versus postoperative health status measures were evaluated by matched-pairs sample t test statistics and post hoc analysis of variance (ANOVA) findings. Results SRS-22 improved from a mean 3.03 points at baseline to 3.21 points at 6 months, 3.71 points at 1 year, and 3.70 points at 2 years post-op. Mean ODI score was 37.0 points pre-op and improved to 27.0 points at 6 months, and 22.8 points at 1 and 2 years post-op. Mean SF-12 physical component score was 33.7 points at baseline, improving to 36.9 points at 6 months, 40.6 points at 1 year, and 40.5 points at 2 years post-op. Paired samples analysis comparing 6-month and 1-year post-op scores showed deterioration for numeric rating scale leg pain (p=0.05). There was a trend for improvement in SF-12 physical component score (p=0.06). Significant improvement between 6 months and 1 year post-op was noted for ODI (p=0.02) and SRS total score (p Conclusions This study supports the application of HRQOL measures, including the deformity-specific SRS-22, as a valuable tool in the assessment of adult deformity patients. Change in outcome score stabilized after the 1-year postoperative interval, for most patients.
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