Systematic and comprehensive analyses of the essential oil of fruits of Xylopia aethiopica (Annonaceae) were conducted. The fruit essential oil was obtained in 0.42% yield. The gas chromatographic-mass spectrometric (GC–MS) analyses showed that the essential oil comprised mainly of monoterpenoids with 1,8–cineole (15.15%) being the most prominent compound. Sabinene (6.6%) and terpinen-4-ol (4.1%) were present in moderately significant amounts. The sesquiterpenoid contents identified were β-elemene (1.26%) and caryophyllene oxide (3.83%).