分子成像
质谱成像
化学
材料科学
光谱学
表征(材料科学)
化学成像
生物医学工程
作者
Nadine Vogler,Sandro Heuke,Thomas Bocklitz,Michael Schmitt,Jürgen Popp
标识
DOI:10.1146/annurev-anchem-071114-040352
摘要
Advanced optical imaging technologies have experienced increased visibility in medical research, as they allow for a label-free and nondestructive investigation of tissue in either an excised state or living organisms. In addition to a multitude of ex vivo studies proving the applicability of these optical imaging approaches, a transfer of various modalities toward in vivo diagnosis is currently in progress as well. Furthermore, combining optical imaging techniques, referred to as multimodal imaging, allows for an improved diagnostic reliability due to the complementary nature of retrieved information. In this review, we provide a summary of ongoing multifold efforts in multimodal tissue imaging and focus in particular on in vivo applications for medical diagnosis. We also discuss the advantages and potential limitations of the imaging methods and outline opportunities for future developments.
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