医学
头皮
淋巴瘤
强的松
病理
长春新碱
环磷酰胺
切碎
美罗华
病态的
甲氨蝶呤
弥漫性大B细胞淋巴瘤
皮肤病科
化疗
内科学
作者
Biswanath Behera,Aparna Palit,AshishKumar Nayak,Ashutosh Panigrahi,Pritinanda Mishra,Madhusmita Sethy
标识
DOI:10.4103/ijd.ijd_783_20
摘要
Primary cutaneous diffuse large B-cell lymphoma-leg type (PCDLBCL-LT) is characterized by diffuse monotonous proliferation of centroblasts and immunoblasts. It commonly presents as erythematous to violaceous nodules on one or both the legs and has a poor prognosis. We report the clinico-dermoscopic-pathological features and therapeutic response of a rare case of PCDLBCL-LT in a 62-year-old diabetic man, who presented with multifocal plaques, one lobulated and two arcuate-shaped, on the face and scalp. During the investigation, one of the plaques had eroded the underlying bone without any evidence of malignant cells in the cerebrospinal fluid. He was successfully treated with R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) along with intrathecal methotrexate.
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