Direct Reductive Arylation of Imines with Electron-Deficient (Hetero) Arenes via Electrosynthesis to Access Benzylic Amines

In this paper, a direct access to benzylic amines from imines and electron-deficient (hetero) arenes via electrochemical radical-radical cross-coupling is described. The reaction has the characteristics of the wide range of substrates, excellent functional group tolerance, metal-free and highly atom-economical. The insensitivity to air and moisture makes this synthetic strategy more efficient for the construction of various benzylic amine derivatives.