Recent Advancements in Nanopharmaceuticals for Novel Drug Delivery Systems

透皮 药物输送 纳米技术 药品 生物利用度 药理学 医学 生化工程 风险分析(工程) 材料科学 工程类
作者
Kai Bin Liew,Ee Va Koh,Xue Er Kong,Nurdina Aleyah Ismail,Rabiatul Adawiyah Abu Bakar,Phei Er Kee,Syed Haroon Khalid,Hiu Ching Phang
出处
期刊:Pharmaceutical nanotechnology [Bentham Science Publishers]
卷期号:13 (2): 271-286 被引量:1
标识
DOI:10.2174/0122117385324246240826042254
摘要

Nanoparticles have found applications across diverse sectors, including agriculture, food, cosmetics, chemicals, mechanical engineering, automotive, and oil and gas industries. In the medical field, nanoparticles have garnered considerable attention due to their great surface area, high solubility, rapid dissolution, and enhanced bioavailability. Nanopharmaceuticals are specifically designed to precisely deliver drug substances to targeted tissues and cells, aiming to optimize therapeutic efficacy while minimizing potential adverse effects. Furthermore, nanopharmaceuticals offer advantages, such as expedited therapeutic onset, reduced dosages, minimized variability between fed and fasted states, and enhanced patient compliance. The increasing interest in nanopharmaceuticals research among scientists and industry stakeholders highlights their potential for various medical applications from disease management to cancer treatment. This review examines the distinctive characteristics of ideal nanoparticles for efficient drug delivery, explores the current types of nanoparticles utilized in medicine, and delves into the applications of nanopharmaceuticals, including drug and gene delivery, as well as transdermal drug administration. This review provides insights into the nanopharmaceuticals field, contributing to the development of novel drug delivery systems and enhancing the potential of nanotechnology in healthcare.
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