医学
肉芽肿伴多发性血管炎
杜皮鲁玛
耐火材料（行星科学）
内科学
嗜酸性
强的松
血管炎
嗜酸性粒细胞增多
不利影响
生活质量（医疗保健）
鼻息肉
胃肠病学
皮肤病科
嗜酸性粒细胞增多症
哮喘
病理
疾病
护理部
物理
天体生物学
作者
Roberto Padoan,F. Davanzo,Luca Iorio,Tommaso Saccardo,Giuseppe Roccuzzo,Sonny Zampollo,Piero Nicolai,Andrea Doria,Giancarlo Ottaviano
标识
DOI：10.1093/rheumatology/keae554
摘要
Eosinophilic granulomatosis with polyangiitis (EGPA) is frequently associated with refractory chronic rhinosinusitis with nasal polyps (CRSwNP), despite current treatments. Dupilumab demonstrated efficacy in the treatment of severe and uncontrolled CRSwNP, with improvements in patient-reported outcome measures and in objective measurements. This study aims to evaluate efficacy and safety of dupilumab in refractory CRSwNP in EGPA patients.
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