Metabolic Acidity/H2O2 Dual‐Cascade‐Activatable Molecular Imaging Platform toward Metastatic Breast Tumor Malignancy

Fluorescence imaging in the second near-infrared window (NIR-II) is crucial for accurate tumor diagnosis, offering superior resolution and penetration capabilities. Current NIR-II probes are limited by either being "always on" or responding to one stimulus, leading to low signal-to-noise ratios and potential false positives. We introduced a dual-lock-controlled probe, HN-PBA, activated by both H