Comparative effects of different sugar substitutes: Mogroside V, stevioside, sucralose, and erythritol on intestinal health in a type 2 diabetes mellitus mouse

Mogroside V (MOG) improves type 2 diabetes mellitus (T2DM) mice gut health via PI3K/AKT and NF-κB, while stevioside (ST) mainly regulates NF-κB. Erythritol (ERT) has minimal benefits. Sucralose (TGS) and sucrose (SUC) harm colon microbiota.