医学
纤维化
信号转导
兴奋剂
内分泌学
癌症研究
内科学
克罗恩病
受体
细胞生物学
生物
疾病
作者
Weijun Ou,W. Yaosheng,Weimin Xu,Zhebin Hua,Xiaolei Wang,Wensong Ge,Wenjun Ding,Yingwei Chen,Chen‐Ying Liu,Peng Du
标识
DOI:10.1093/ecco-jcc/jjaf084
摘要
The antifibrotic effects of PGI2-PTGIR signaling are impaired in CD. Restoring PGI2-PTGIR signaling is a pharmacologically tractable and cell-selective approach to targeting YAP/TAZ via PTGIR, which reverses intestinal fibrosis.
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