肾素-血管紧张素系统
受体
内皮功能障碍
化学
药理学
内分泌学
细胞生物学
生物
生物化学
血压
作者
Lachlan G. Schofield,Juyi Zhao,Yu Wang,Sarah J. Delforce,Saije K. Endacott,Eugenie R. Lumbers,Dan Ma,Kirsty G. Pringle
标识
DOI:10.1016/j.ejphar.2025.177601
摘要
Elevated s(P)RR induces endothelial dysfunction at least partially through AT1R. PRO20 prevents s(P)RR-AT1R formation, suggesting it could be an effective therapeutic for preeclampsia and conditions requiring renin-angiotensin system suppression.
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