表面改性
化学
羧酸盐
苯
反应性(心理学)
甲苯
产量(工程)
碳纤维
铜
氢
药物化学
组合化学
有机化学
无机化学
材料科学
医学
替代医学
物理化学
病理
复合数
冶金
复合材料
作者
Fanji Kong,Shusen Chen,Junqi Chen,Chang Liu,Weihao Zhu,Diane A. Dickie,William L. Schinski,Sen Zhang,Daniel H. Ess,T. Brent Gunnoe
出处
期刊:Science Advances
[American Association for the Advancement of Science (AAAS)]
日期:2022-08-26
卷期号:8 (34)
被引量:9
标识
DOI:10.1126/sciadv.add1594
摘要
We report carbon-hydrogen acetoxylation of nondirected arenes benzene and toluene, as well as related functionalization with pivalate and 2-ethylhexanoate ester groups, using simple copper(II) [Cu(II)] salts with over 80% yield. By changing the ratio of benzene and Cu(II) salts, 2.4% conversion of benzene can be reached. Combined experimental and computational studies results indicate that the arene carbon-hydrogen functionalization likely occurs by a nonradical Cu(II)-mediated organometallic pathway. The Cu(II) salts used in the reaction can be isolated, recycled, and reused with little change in reactivity. In addition, the Cu(II) salts can be regenerated in situ using oxygen and, after the removal of the generated water, the arene carbon-hydrogen acetoxylation and related esterification reactions can be continued, which leads to a process that enables recycling of Cu(II).
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