Glatiramer acetate induces mast cell degranulation via MRGPRX2, implications for local and systemic adverse reactions

家庭医学 图书馆学 医学 计算机科学
作者
Shaswati Chaki,Aetas Amponnawarat,Brett Levenstein,Yvonne Hui,Carole A. Oskeritzian,Hydar Ali
出处
期刊:Allergy [Wiley]
被引量:1
标识
DOI:10.1111/all.15978
摘要

AllergyEarly View LETTER Glatiramer acetate induces mast cell degranulation via MRGPRX2, implications for local and systemic adverse reactions Shaswati Chaki, Shaswati Chaki Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USASearch for more papers by this authorAetas Amponnawarat, Aetas Amponnawarat orcid.org/0009-0005-4989-2761 Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA Department of Family and Community Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, ThailandSearch for more papers by this authorBrett Levenstein, Brett Levenstein Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USASearch for more papers by this authorYvonne Hui, Yvonne Hui Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South California, USASearch for more papers by this authorCarole Oskeritzian, Carole Oskeritzian orcid.org/0000-0003-1380-9186 Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South California, USASearch for more papers by this authorHydar Ali, Corresponding Author Hydar Ali [email protected] orcid.org/0000-0001-9190-1960 Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA Correspondence Hydar Ali, Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104, USA. Email: [email protected]Search for more papers by this author Shaswati Chaki, Shaswati Chaki Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USASearch for more papers by this authorAetas Amponnawarat, Aetas Amponnawarat orcid.org/0009-0005-4989-2761 Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA Department of Family and Community Dentistry, Faculty of Dentistry, Chiang Mai University, Chiang Mai, ThailandSearch for more papers by this authorBrett Levenstein, Brett Levenstein Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USASearch for more papers by this authorYvonne Hui, Yvonne Hui Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South California, USASearch for more papers by this authorCarole Oskeritzian, Carole Oskeritzian orcid.org/0000-0003-1380-9186 Department of Pathology, Microbiology and Immunology, University of South Carolina School of Medicine, Columbia, South California, USASearch for more papers by this authorHydar Ali, Corresponding Author Hydar Ali [email protected] orcid.org/0000-0001-9190-1960 Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA Correspondence Hydar Ali, Department of Basic and Translational Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, PA 19104, USA. Email: [email protected]Search for more papers by this author First published: 14 December 2023 https://doi.org/10.1111/all.15978Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Open Research DATA AVAILABILITY STATEMENT Data sharing is not applicable to this article as no new data were created or analyzed in this study. Supporting Information Filename Description all15978-sup-0001-DataS1.docxWord 2007 document , 43.3 KB Data S1. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. REFERENCES 1Roseler S, Leufgens F, Merk HF, et al. False-positive test results in diagnosing allergy to glatiramer acetate: case report and a systematic literature review. Immun Inflamm Dis. 2020; 8: 847-853. 10.1002/iid3.357 PubMedWeb of Science®Google Scholar 2Bains SN, Hsieh FH, Rensel MR, et al. Glatiramer acetate: successful desensitization for treatment of multiple sclerosis. Ann Allergy Asthma Immunol. 2010; 104: 321-325. 10.1016/j.anai.2009.11.040 CASPubMedWeb of Science®Google Scholar 3Kolkhir P, Ali H, Babina M, et al. MRGPRX2 in drug allergy: what we know and what we do not know. J Allergy Clin Immunol. 2023; 151: 410-412. 10.1016/j.jaci.2022.09.004 CASWeb of Science®Google Scholar 4Plum T, Wang X, Rettel M, Krijgsveld J, Feyerabend TB, Rodewald HR. Human mast cell proteome reveals unique lineage, putative functions, and structural basis for cell ablation. Immunity. 2020; 52: 404-416.e5. 10.1016/j.immuni.2020.01.012 CASPubMedWeb of Science®Google Scholar 5Bawazir M, Amponnawarat A, Hui Y, Oskeritzian CA, Ali H. Inhibition of MRGPRX2 but not FcepsilonRI or MrgprB2-mediated mast cell degranulation by a small molecule inverse receptor agonist. Front Immunol. 2022; 13:1033794. 10.3389/fimmu.2022.1033794 CASWeb of Science®Google Scholar 6Teitelbaum D, Milo R, Arnon R, Sela M. Synthetic copolymer 1 inhibits human T-cell lines specific for myelin basic protein. Proc Natl Acad Sci U S A. 1992; 89: 137-141. 10.1073/pnas.89.1.137 CASPubMedWeb of Science®Google Scholar Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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