医学
安慰剂
动态血压
回廊的
血压
随机化
加药
随机对照试验
临床终点
醛固酮
泌尿科
内科学
替代医学
病理
作者
George L. Bakris,Manish Saxena,Anil Gupta,Fadi Chalhoub,Jong-Tae Lee,Daniel Stiglitz,Nune Makarova,Nitender Goyal,Weinong Guo,Dion Zappe,Akshay S. Desai,George Carr,Christopher Case,Lauren Hubert Jaeger,Lisa Bruns,Ginger Stratman,Christy Kidwell,Suzin Cunningham,Nicholas Piccone,Mordecai Klein
出处
期刊:JAMA
[American Medical Association]
日期:2024-02-16
卷期号:331 (9): 740-740
被引量:54
标识
DOI:10.1001/jama.2024.0728
摘要
Angiotensinogen is the most upstream precursor of the renin-angiotensin-aldosterone system, a key pathway in blood pressure (BP) regulation. Zilebesiran, an investigational RNA interference therapeutic, targets hepatic angiotensinogen synthesis.
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