黄芩
生物
计算生物学
蛋白质组
背景(考古学)
韧皮部
木质部
次生代谢物
类黄酮生物合成
类黄酮
植物
转录组
基因
生物化学
中医药
基因表达
病理
古生物学
替代医学
抗氧化剂
医学
作者
Dandan Guo,Zhenyu Zhu,Zhe Wang,Feng Fu,Qing Cao,Zhewei Xia,Xin‐Lei Jia,Diya Lv,Ting Han,Xiaofei Chen
摘要
Abstract Scutellaria baicalensis Georgi, also known as Huang-Qin in Traditional Chinese Medicine, is a widely used herbal remedy due to its anticancer, antivirus, and hepatoprotective properties. The S. baicalensis genome was sequenced many years ago, by contrast, the proteome as the executer of most biological processes of S. baicalensis in the aerial parts, as well as the secondary structure of the roots (xylem, phloem and periderm) is far less comprehensively characterized. Here, we attempt to depict the molecular landscape of the non-model plant S. baicalensis through a multi-omics approach, with the goal of constructing a highly informative and valuable reference dataset. Furthermore, we provide an in-depth characterization dissection to explain two distinct flavonoid biosynthesis pathways existed in aerial part and root, respectively, at the protein and phosphorylated protein level. Our study provides detailed spatial proteomic and phosphoproteomic information in the context of secondary structures, with implications for the molecular profiling of secondary metabolite biosynthesis in non-model medicinal plants.
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