Effect of Stent Porosity, Platelet Function Test Usage, and Dual Antiplatelet Therapy Duration on Clinical and Radiographic Outcomes After Stenting for Cerebral Aneurysms: A Meta-Analysis

医学 支架 狭窄 多孔性 内科学 闭塞 放射科 心脏病学 外科 材料科学 复合材料
作者
Sarah-Marie Gonzalez,Jordan Iordanou,William Adams,John T. Tsiang,Joseph Frazzetta,Miri Kim,Elhaum G. Rezaii,Nathan C. Pecoraro,Brandon M Zsigray,J Simon,Jehad Zakaria,Ignacio Jusué-Torres,Daphne Li,Daniel M. Heiferman,Joseph C. Serrone
出处
期刊:World Neurosurgery [Elsevier BV]
卷期号:171: 159-166.e13 被引量:1
标识
DOI:10.1016/j.wneu.2022.12.055
摘要

The use of stents with various porosities for treating cerebral aneurysms requires dual antiplatelet therapy (DAPT) without clear guidelines on the utility of platelet function tests (PFTs) and the duration of DAPT. We sought to determine the effects of stent porosity, PFT usage, and DAPT duration on the radiographic and clinical outcomes after stenting of cerebral aneurysms.PubMed was searched on March 29, 2021 for studies of cerebral aneurysm stenting that had specified the stent type and DAPT duration. A random effects meta-analysis was used to measure the prevalence of nonprocedural thrombotic and hemorrhagic events, clinical outcomes, aneurysm occlusion, and in-stent stenosis stratified by stent porosity, PFT usage, and DAPT duration.The review yielded 105 studies (89 retrospective and 16 prospective) with 117 stenting cohorts (50 high porosity, 17 intermediate porosity, and 50 low porosity). In the high-, intermediate-, and low-porosity stenting cohorts, PFT usage was 26.0%, 47.1%, and 62.0% and the mean DAPT duration was 3.51 ± 2.33, 3.97 ± 1.92, and 5.18 ± 2.27 months, respectively. The intermediate-porosity stents showed a reduced incidence of hemorrhagic events (π = 0.32%) compared with low-porosity stents (π = 1.36%; P = 0.01) and improved aneurysm occlusion (π = 6.18%) compared with high-porosity stents (π = 14.42%; P = 0.001) and low-porosity stents (π = 11.71%; P = 0.04). The prevalence of in-stent stenosis was lower for the intermediate-porosity (π = 0.57%) and high-porosity (π = 1.51%) stents than for the low-porosity stents (π = 3.30%; P < 0.05). PFT use had resulted in fewer poor clinical outcomes (π = 3.54%) compared with those without PFT use (π = 5.94%; P = 0.04). The DAPT duration had no effect on the outcomes.In the present meta-analysis, which had selected for studies of cerebral aneurysm stenting that had reported the DAPT duration, intermediate-porosity stents and PFT use had resulted significantly improved outcomes. No effect of DAPT duration could be detected.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
2秒前
youcclucky发布了新的文献求助10
2秒前
熊熊发布了新的文献求助10
4秒前
辛勤香岚完成签到,获得积分10
5秒前
Dongjie完成签到,获得积分10
5秒前
Hello应助科研通管家采纳,获得10
6秒前
所所应助科研通管家采纳,获得10
6秒前
美好乐松应助科研通管家采纳,获得10
7秒前
迟大猫应助科研通管家采纳,获得10
7秒前
小蘑菇应助科研通管家采纳,获得10
7秒前
迟大猫应助科研通管家采纳,获得10
7秒前
迟大猫应助科研通管家采纳,获得10
7秒前
迟大猫应助科研通管家采纳,获得10
7秒前
迟大猫应助科研通管家采纳,获得10
7秒前
爆米花应助科研通管家采纳,获得10
7秒前
迟大猫应助科研通管家采纳,获得10
7秒前
FashionBoy应助科研通管家采纳,获得10
7秒前
研友_VZG7GZ应助科研通管家采纳,获得10
7秒前
爆米花应助科研通管家采纳,获得10
7秒前
CipherSage应助科研通管家采纳,获得10
8秒前
李健应助科研通管家采纳,获得10
8秒前
美好乐松应助科研通管家采纳,获得10
8秒前
1+1应助科研通管家采纳,获得10
8秒前
香蕉觅云应助科研通管家采纳,获得10
8秒前
hhhhhhmt完成签到 ,获得积分10
8秒前
1+1应助科研通管家采纳,获得10
8秒前
lulu应助科研通管家采纳,获得10
8秒前
852应助科研通管家采纳,获得10
8秒前
华仔应助科研通管家采纳,获得10
8秒前
8秒前
着急的大米完成签到 ,获得积分10
8秒前
CodeCraft应助科研通管家采纳,获得10
8秒前
9秒前
情怀应助Rosaline采纳,获得20
10秒前
Hello应助喜乐采纳,获得30
11秒前
我爱看文献完成签到 ,获得积分10
13秒前
星星完成签到 ,获得积分10
13秒前
小林完成签到,获得积分10
13秒前
杨大夫发布了新的文献求助10
16秒前
高分求助中
Production Logging: Theoretical and Interpretive Elements 2700
Neuromuscular and Electrodiagnostic Medicine Board Review 1000
こんなに痛いのにどうして「なんでもない」と医者にいわれてしまうのでしょうか 510
The First Nuclear Era: The Life and Times of a Technological Fixer 500
Unusual formation of 4-diazo-3-nitriminopyrazoles upon acid nitration of pyrazolo[3,4-d][1,2,3]triazoles 500
岡本唐貴自伝的回想画集 500
Distinct Aggregation Behaviors and Rheological Responses of Two Terminally Functionalized Polyisoprenes with Different Quadruple Hydrogen Bonding Motifs 450
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3671598
求助须知:如何正确求助?哪些是违规求助? 3228309
关于积分的说明 9779385
捐赠科研通 2938622
什么是DOI,文献DOI怎么找? 1610143
邀请新用户注册赠送积分活动 760547
科研通“疑难数据库(出版商)”最低求助积分说明 736093