Targeting Mettl14 Using an RNA‐Targeting Clustered Regularly Interspaced Short Palindromic Repeat‐ High‐Fidelity Cas13x System Attenuates Doxorubicin‐Induced Cardiotoxicity

Our results suggest that the CRISPR-hfCas13x system has the potential for generating exercise mimetics. Mimicking exercise by RNA-targeting Mettl14 suppression could be a therapeutic strategy for doxorubicin-induced cardiotoxicity.