系统性红斑狼疮
医学
降级(电信)
免疫学
自身免疫性疾病
红斑狼疮
免疫系统
突变
疾病
自身免疫
化学
生物
遗传学
作者
Tadej Avčin,Andreas Reiff,Maša Bizjak,Barbara Jenko Bizjan,Tina Vesel Tajnšek,Maruša Debeljak,Tyler Artner,Bernd Jilma,Christian Lood,Abdul Hakkim,Tobias A. Fuchs
摘要
Recombinant DNASE1L3 therapy reduced symptoms in a patient with severe lupus with DNASE1L3 deficiency. Antidrug antibodies caused effects to wane, but findings support NET-targeted therapy as a nonimmunosuppressive approach.
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