Main textMajor haemorrhage is a leading cause of morbidity and mortality in various medical settings including trauma, vascular emergencies, gastrointestinal bleeding and obstetric complications.Crucial aspects of optimising the pre-and early in-hospital management of these patients remain scientifically unresolved.In this collection of articles, the Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine presents a series of studies that aim to enhance our understanding of early transfusion strategies in haemorrhagic shock.