A novel eco‐friendly on‐water protocol for the synthesis of 2,2‐disubstituted 2,3‐dihydro‐1H‐perimidines

Abstract An efficient green on‐water protocol for the synthesis of 2,2‐disubstituted 2,3‐dihydro‐1 H ‐perimidines is demonstrated. The reaction used safer p ‐toluenesulfonic acid (PTSA) as a catalyst on water at 80°C, for 2 hours affording a novel method for the synthesis of various disubstituted perimidines in moderate to excellent yields.