Highly efficient asymmetric reduction of ketopantolactone to d-(−)-pantolactone by Escherichia coli cells expressing recombinant conjugated polyketone reductase and glucose dehydrogenase in a fed-batch biphasic reaction system

Enantiopure d-(−)-pantolactone was efficiently synthesized by Escherichia coli cells expressing recombinant CduCPR and BsuGDH in a fed-batch biphasic reaction system.