DPPH
广告
化学
乙酰胆碱酯酶
阿布茨
抗氧化剂
阿切
药理学
IC50型
髓系白血病
对接(动物)
丁酰胆碱酯酶
生物化学
酶
体外
医学
免疫学
护理部
作者
Tingting Liu,Lixia Cao,Tingting Zhang,Huan Fu
标识
DOI:10.1080/13813455.2020.1828483
摘要
In this research, we explored their capacity for Narcissoside antioxidant and anticholinergic, antidiabetic, and anti-acute myeloid leukaemia. Narcissoside's antioxidant activities were elucidated by the use of various bioanalytical assays. Narcissoside's radical scavenging activities were evaluated by DPPH• and ABTS•+ scavenging activities. On the other hand, IC50 values were calculated for DPPH•, and ABTS•+ scavenging, acetylcholinesterase, and α-glucosidase inhibition effects of narcissoside. IC50 values narcissoside, as 11.54 nM for AChE and 65.58 nM for α-glucosidase were calculated with % Activity-[Inhibitory] graphs. Then, ADME/T analysis of narcissoside molecule was performed to calculate the drug becoming parameters.
科研通智能强力驱动
Strongly Powered by AbleSci AI