A multifunctional nanoplatform delivering carbon monoxide and a cysteine protease inhibitor to mitochondria under NIR light shows enhanced synergistic anticancer efficacy

A fluorescent nanoplatform covalently functionalized with a Mn–CO donor and a Ru( ii )-caged cysteine protease inhibitor delivers CO and the enzyme inhibitor to mitochondria upon NIR light irradiation, showing enhanced synergistic anticancer efficacy.