Biological roles of sulfur dioxide and sulfite in the regulation of mitochondrial viscosity

Herein, a NIR fluorescent probe has been developed for visualization of the roles of SO₂/SO₃^2- in mitochondrial viscosity. The results showed that SO₃^2- would increase mitochondrial viscosity and decrease mitochondrial membrane potential (MMP). However, increasing SO₂ stimulation decreased mitochondrial viscosity and caused inconspicuous MMP changes.