检出限
抗坏血酸
尿酸
化学
选择性
电化学
电化学气体传感器
色谱法
胆固醇
材料科学
生物化学
电极
食品科学
物理化学
催化作用
作者
Neha Thakur,Debaprasad Mandal,Tharamani C. Nagaiah
摘要
A novel non-enzymatic electrochemical sensor was constructed to achieve a highly selective and ultrasensitive detection of cholesterol to address the problems related to serious coronary heart disease. The NiVP/Pi-based sensor exhibited ultra-high sensitivity of 5510.18 μA μM-1 cm-2 and 36.8 μA μM-1 cm-2 for 1 nM to 10 μM and 100 μM to 10 mM of cholesterol, respectively, with an ultra-low detection limit of 1 aM, along with superior selectivity for cholesterol when exposed to various interferents such as ascorbic acid, glucose and uric acid. Also, a novel NiVP/Pi-based flexible sensor coated onto Whatman filter paper was developed and displayed superior sensitivity, even with a human blood serum sample at physiological pH.
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