American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis

These practice guideline recommendations for the initial management of AP were developed using the GRADE framework and in adherence with the standards for guideline development set forth by the Institute of Medicine for the creation of trustworthy guidelines.11American Gastroenterological Association Institute Clinical Practice Guideline Development Process. http://www.gastro.org/guidelines/guidelines-policies. Accessed July 31, 2017.Google Scholar, 13Institute of MedicineClinical Practice Guidelines We Can Trust. The National Academies Press, Washington, DC2011Google Scholar These guidelines are intended to reduce practice variation and promote high-quality and high-value care for patients with AP. Current evidence supports the benefit of goal-directed fluid resuscitation, early oral feeding, and enteral rather than parenteral nutrition, in all patients with AP. Our evidence profiles also support the benefit of same-admission cholecystectomy for patients with biliary pancreatitis, and brief alcohol intervention for patients with alcohol-induced pancreatitis. In contrast, current evidence does not support a benefit for the routine use of prophylactic antibiotics in predicted severe AP or routine ERCP in patients with AP without accompanying cholangitis.