Local Infiltration Analgesia with Anterior Total Hip Arthroplasty under General Anaesthesia does Reduce Opioids Consumption and Pain: A Randomized, Double- Blind, Placebo-Controlled Trial Involving 106 Patients

Local infiltration analgesie (LIA) in total hip arthroplasty (THA) is widely used to reduce severe postoperative pain which may delay recovery and rehabilitation [1,2]. The goal is to achieve adequate pain relief in combination with optimal muscle function, allowing early mobilization [3-7]. Multimodal analgesia in combination with LIA is meant to reduce the need of opiods and its side effects (nausea, vomiting, reduced gut mobility and urinary retention) to facilitate fast and safe recovery and enhance rehabilitation [8].