A series of new 4,6-bis(azolyl/azinyl/azepinyl)resorcinols was synthesized in a combinatorial manner besides, (2E,2'E)-4,6-bis [3-(aminophenylsubstituted)prop-2-en-1-oxo-1-yl]resorcinols were also obtained.Heterocyclizationnitrogen-containing binucleophiles afforded the target compounds.All the newly synthesized compounds were characterized by spectral tools.Resorcinol possesses unique structural characteristics for developing drug compounds exhibiting chemical structures and properties suitable for treating various human diseases. 1-3Chemical compounds derived from the resorcinol derivatives can be potent and effective medicines.Resorcinol derivatives have been used by the major drug companies to develop new drugs, and also for the manufacture of existing therapeutic compounds. 4-6Enaminones are versatile reagents and their utilities in heterocyclic synthesis