Multivariate regression analysis on early death after orthotopic liver transplantation

Objective To identify the risk factors relative to early death after orthotopic liver transplantation.Methods Clinical data of 37 adult patients undergoing liver transplantation were retrospectively collected. They were divided into two groups: the survival group (survival time≥30 days, n =27) and dead group (survival time30 days, n =10). The relationship between multivariate risk factors and early death after orthotopic liver transplantation was analyzed by stepwise logistic regression. Results Survival rate was 73% and early mortality was 27 %. Apache Ⅲ scores, preoperative serum creatinine level and interoperative bleeding amount had significant independent association with early death with the R = 0.1841 , 0.2056 and 0.3738 respectively.Conclusion Apache Ⅲ scores, preoperative serum creatinine level and interoperative bleeding amount were significent risk factors responsible for early death after orthotopic liver transplantation. To improve the recipient's preoperative critical condition and renal function and to decrease interoperative bleeding amount can ameliorate the early mortality after orthotopic liver transplantation.