The Hemostatic Study of Shuning Sponge in Hepatic Trauma of SD Rats

Objective To determine the hemostatic effect of Shuning sponge. Method 72 SD rats with hemorrhage surffered from hepatic trauma were randomized into three groups and managed with different hemostatic agent: Shuning sponge group (n=24), oxidized cellulose group (n=24, control groupⅠ) and gelatin sponge group (n=24, control groupⅡ). Hemostatic time and total blood loss were recorded and compared in the three groups under different coagulation states. Results ①Under different coagulation states, the hemostatic time in Shuning sponge group was significantly shorter than those in the other two groups ( P 0.05). ②Before and after anti coagulation therapy, there was no significant difference of hemostatic ability in Shuning sponge group, but there were significant differences in the control groups ( P 0.05). Conclusion In the hepatic traumatic hemorrhage models Shuning sponge is superior than the other two agents in hemostasis under different coagulation states.