医学
肺毒性
环磷酰胺
博莱霉素
肺炎
放射治疗
肺纤维化
放化疗
间质性肺病
中止
肺
毒性
呼吸衰竭
急性呼吸窘迫综合征
病理
内科学
化疗
胃肠病学
作者
R Riou,P. Duvillard,R Touraine
出处
期刊:PubMed
日期:1982-01-01
卷期号:38 (1): 57-62
摘要
Two patients with small cell carcinoma of the lung treated by chemoradiotherapy developed, diffuse interstitial pneumonitis after 7 and 21 months of treatment while in complete remission of their malignant disease. One patient died after an acute respiratory distress syndrome, but the second improved after steroid therapy and discontinuation of cytotoxic therapy. Pulmonary toxicity appeared to be related to cyclophosphamide therapy, but radiation therapy could have potentiated cyclophosphamide toxicity as it has been shown in bleomycin lung disease.
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