Objective:The study aimed to determine primary speciation and dissolution rate of trace elements in 2 kinds of Prunella vulgaris by flame atomic absorption spectrometry.Method: The aqueous solution of Prunella vulgaris was separated into three species including the dissoluble species,suspensible solid and residue by 0.45 μm membrane filter and four layers filter gauze.Result:The ratios of water-soluble state in aqueous solution of the prunella vulgaris were quite different in each other and the dissolution rates of elements were in the range of 0.00 %~78.86 %.Conclusion:The study had provided reference for further researches in the prunella vulgaris.The study provides reference information for further study of the relationship between the trace element and themedicine efficacy in Prunella vulgaris.