The Role of HSP27 in Regulating Apoptosis

Heat shock proteins(HSPs)are ubiquitous in organisms,with high conservative in organic evolution and expression in physiological condition or stress response.HSP27 which correlated with increasing cell survival in stress response is significant one of the HSPs family.It has been shown that HSP27 regulates apoptosis to prevent cell death by interacting with a large number of important proteins in apoptotic signal pathway.