Cutaneous lupus erythematosus is a relatively mild subtype in the spectrum of lupus erythematosus. The management of cutaneous lupus erythematosus is different from that of systemic lupus erythematosus (SLE). Topical therapies are usually useful in the treatment of cutaneous lupus erythematosus. When lesions are not controlled with topical corticosteroids, intralesional corticosteroids are often indicated. Antimalarial, corticosteroid ,retinoids are mainstays in systemic therapy, and cytotoxic agents and thalidomide are effective for patients who are resistant to routine therapies. Pulsed dye laser and ultraviolet therapy can be helpful in the treatment of cutaneous lupus erythematosus.