The protective effect of astaxanthin on HaCaT keratinocytes injured by oxidative stress

Objective To study the protective effect of astaxanthin on HaCaT keratinocytes injured by UVA induced oxidative stress.Methods Human keratinocytes HaCat were used as an experimental model in vitro.Cell viability was determined by MTT and the amounts of SOD、GSH-px、MDA were measured by biochemical methods.Results Astaxanthin increased the cell viability、SOD and GSHpx,and decreased MDA level of HaCaT keratinocytes.Conclusion Astaxanthin has protective effect on HaCaT keratinocytes injured by UVA induced oxidative stress.