Localized linear epidermolytic epidermal nevus of male genitalia with a recurrent keratin 10 mutation, p.Arg156His

Epidermal nevus presents histologically with epidermal hyperplasia, hyperkeratosis, papillomatosis and, rarely, epidermolytic hyperkeratosis or granular degeneration. Mutations of keratin 1 and keratin 10 genes have been reported in epidermolytic ichthyosis [1], (previously called bullous congenital ichthyosiform erythroderma) [2], which shows epidermolytic hyperkeratosis. Genetic mosaicism has been reported in epidermal nevus with epidermolytic hyperkeratosis [3], where mutations of keratin 1 or [...]