Background Ankle fractures are one of the most common injuries treated by orthopaedic surgeons. On the basis of foot and the direction of the force many classification have been described, the most popular being that of Lauge Hansen. Management of this fracture depends on careful identification of extent of bony injury as well as soft tissue and ligamentous damage. In ankle fracture, operative treatment internal fixation with plate provides good result. So we decided to study the role of internal fixation in treatment of ankle fracture. Aims and Objectives To study the role of internal fixation with plate in treatment of ankle fracture with restoration of normal ankle function. Materials and Methods This is a prospective study of 50 cases of ankle fracture treated with open reduction and internal fixation with plate (1/3 tubular plate) at tertiary care teaching hospital carried out from May 2012 to July 2014. Criteria for assessment of quality of reduction used are the same as that of Burnwell and Charnley. Results Maximum patients belong to age group 21–40 (64%). Among them, 45 (90%) patients were male and 5 (10%) were females. Out of 50 patients treated, 30 (60%) patients obtained excellent results, 14 (28%) obtained good results and 6 (12%) had poor outcome. Conclusion The keyword of success is good anatomical reduction and rigid fixation of the fracture, irrespective of the classification of the fracture or the mode of injury.