Alteration in white matter tracts in early onset schizophrenia Using Diffusion tensor imaging

The study investigated white matter tracts disruption in early-onset Schizophrenia (EOS). Our finding revealed decreased white matter tracts fractional anisotropy (FA) and increased radial, axial and mean diffusivity in EOS as compared to controls, suggesting thinner packing of axon and fiber bundle. Disrupted white matter fibers may be associated with impaired neurobehavior in EOS.