重编程
生物
体细胞
诱导多能干细胞
细胞生物学
细胞
遗传学
胚胎干细胞
基因
作者
Emily J. Park,Srikanth Kodali,Bruno Di Stefano
出处
期刊:Cell Stem Cell
[Elsevier BV]
日期:2023-04-01
卷期号:30 (4): 335-337
被引量:6
标识
DOI:10.1016/j.stem.2023.03.001
摘要
Small molecule-induced cell fate transitions are characterized by low efficiency and slow kinetics. An optimized chemical reprogramming approach now facilitates the robust and rapid conversion of somatic cells to pluripotent stem cells, unlocking exciting avenues to study and manipulate human cell identity.
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