医学
免疫学
原发性免疫缺陷
肾病综合征
爱泼斯坦-巴尔病毒
胸腔积液
免疫失调
免疫系统
爱泼斯坦-巴尔病毒感染
病毒
胃肠病学
内科学
作者
Diana Rodà,Malka Huici,Sílvia Ricart,Jordi Vila,Clàudia Fortuny,Laia Alsina
标识
DOI:10.1080/20469047.2015.1135561
摘要
Epstein–Barr virus (EBV) infection results in a spectrum of clinical manifestations. The host immune response to EBV plays a key role in the extent and degree of clinical features, which in children under 4 years of age are usually mild, non-specific and self-limiting. A 2-year-old boy in whom no known immune disorder could be found presented with acute acalculous cholecystitis, renal dysfunction with massive proteinuria, ascites, pleural effusion, minimal peripheral oedema and a severe systemic inflammatory response. Improvement occurred after initiation of corticosteroids and antiviral treatment with gancyclovir. In severely symptomatic or complicated EBV infection, a primary immunodeficiency must be suspected. If a primary immunodeficiency has been ruled out, the correct management of severe EBV infection in the immunocompetent host remains controversial.
科研通智能强力驱动
Strongly Powered by AbleSci AI