Factors influencing adult neurogenesis

Studies demonstrate that new cell birth occurs in adult brain,the rate of neurogenesis and the survival of new neurons are regulated by a number of environmental and pharmacological factors.The presence of neural progenitors in the adult mammalian brain raises the possibility that adult neurogenesis exists as a substrate for neural plasticity.Moreover,the continued production of neurons within the adult brain suggests that an understanding of adult neurogenesis may be of therapeutic relevance.In this review the factors influencing adult neurogenesis are discussed.