Synthesis of six-membered cyclic carbamates employing CO2 as building block: A review

Abstract The utilization of carbon dioxide (CO2) as a sustainable and renewable one-carbon (C1) building block in organic synthesis has attracted great attention since it may provide access to profitable chemicals from an abundant, non-toxic, non-flammable and inexpensive resource. Among these transformations, synthesis of biologically and synthetically important six-membered cyclic carbamates employing CO2 as building block represents one of the hottest and attractive research topics in the field. This focus-review survey the available literature on the synthesis of titled compounds from the reaction of various substrates (e.g., γ-amino alcohols, γ-haloamines, homoallylic amines, propargylic amines, o-alkynylanilines) with CO2, by hoping that it will encourage researchers to further thinking and research in this explosively growing field.