聚己内酯
材料科学
石墨烯
纤维接头
极限抗拉强度
生物医学工程
外科
复合材料
纳米技术
医学
聚合物
作者
Shadi Houshyar,Amitava Bhattacharyya,Asma Khalid,Aaqil Rifai,Chaitali Dekiwadia,G. Sathish Kumar,Phong A. Tran,Kate Fox
标识
DOI:10.1002/mabi.202000364
摘要
Abstract The next‐generation sutures should provide in situ monitoring of wound condition such as temperature while reducing surgical site infection during wound closure. In this study, functionalized nanodiamond (FND) and reduced graphene oxide (rGO) into biodegradable polycaprolactone (PCL) are incorporated to develop a new multifunctional suture with such capabilities. Incorporation of FND and rGO into PCL enhances its tensile strength by about 43% and toughness by 35%. The sutures show temperature sensing capability in the range of 25–40 °C based on the shift in zero‐splitting frequency of the nitrogen‐vacancy (NV – ) centers in FND via optically detected magnetic resonance, paving the way for potential detection of infection or excessive inflammation in healing wounds. The suture surface readily coats with antibiotics to reduce bacterial infection risk to the wounds. The new suture thus is promising in monitoring and supporting wound closure.
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