Compare the efficacy of healing in mandibular third-molar sockets using the combination of platelet-rich fibrin and Biograft-HT ® with that of platelet-rich fibrin alone

Aim and Objectives: The aim of this prospective clinical study was to compare the efficacy of a combination of Platelet Rich Fibrin (PRF) and biograft- HT® with that of platelet rich fibrin alone in healing of impacted mandibular third molar sockets after surgical removal of the same. Objectives were to compare the post-operative pain, swelling, trismus, periodontal health distal to mandibular second molar, quality of bone healing at the mandibular third molar socket at various time intervals.Methodology : This was split mouth study where PRF and biograft- HT® was placed on one side of the third molar extraction socket and PRF alone was placed on the other side in 15 patients with bilaterally impacted 3rd molars. Results: There was no statistically significant difference seen in any of the parameters Conclusion: This study does not prove statistically significant improvement in the efficacy of combination of PRF with Biograft- HT® when compared to PRF alone. The addition of Biograft- HT® to PRF increases the cost of the treatment while PRF alone is cost effective as it is prepared with patient“s own blood. Hence, the addition of Biograft- HT® to PRF can”t be recommended based on our study alone.