[Diagnosis of ectopic pregnancy: endometrial biopsy or diagnostic hysteroscopy].

OBJECTIVES: Define indications for endometrial biopsy and diagnostic hysteroscopy in ectopic pregnancy diagnosis. Define the indication of endometrial biopsy and diagnostic hysteroscopy in ectopic pregnancy diagnosis. MATERIALS AND METHODS: This prospective study included 15 women with a poorly localized pregnancy (ectopic or intrauterine localization not identified at ultrasound) who had an abnormal HCG curve and low progesteronemia. RESULTS: In 8 patients, an empty cavity was identified at diagnostic hysteroscopy and the endometrial biopsy was negative. In 2 patients hysteroscopy was non-contributive (pregnancy and intra uterine device with blood in the cavity) and the endometrial biopsy was negative. In 3 patients who had an early abortion hysteroscopy and endometrial biopsy demonstrated villosities. Finally, in 2 patients who had an early abortion hysteroscopy identified villosities and endometrial biopsy was non-contributive. The sensitivity and specificity of hysteroscopy for the diagnosis of EP was 100% but the sensitivity of endometrial biopsy was 50% with a specificity of 100%. CONCLUSION: If pregnancy cannot be correctly localized at ultrasonography, hysteroscopy appears to be better than endometrioal biopsy to discriminate between EP and early abortion.