Abstract 693: Nox4 Mediates Cardiac Fibrosis while p47phox-based Nox2 is Required for the Inflammatory Response to Angiotensin II in Murine Cardiac Fibroblasts

Reactive oxygen species (ROS) mediate cardiac fibrosis induced by angiotensin II (Ang II) and NADPH oxidases (Nox) are a major source of ROS. In vitro, activation of Nox2 by Ang II requires the cyt...