苦味
药品
溶解
患者依从性
材料科学
医学
药物输送
纳米技术
化学
剂型
药理学
溶解试验
品味
有机化学
食品科学
急诊医学
生物制药分类系统
作者
Ankita Chaturvedi,Pranati Srivastava,Sunita Yadav,Mayank Bansal,Garima Garg,Pramod Kumar Sharma
标识
DOI:10.2174/156720111795768022
摘要
Fast-dissolving drug delivery systems have been developed as an alternative to conventional dosage form as an oral means of drug delivery in case of chronic conditions. Now a day's fast dissolving films are preferred over conventional tablets and capsules for masking the taste of bitter drugs to increase the patient compliance. Fast dissolving films consist of a very thin oral strip which dissolves in less than one minute when placed on the tongue. Dissolvable oral thin films are in the market since past few years in the form of breath strips and are widely accepted by consumers for delivering vitamins, vaccines and other drug products. The various manufacturing techniques for the preparation of films have also been detailed in the review. The present review details most of the patents on such fast dissolving films in recent years. A brief study has been made on various parameters which are used to evaluate such films. In case of chronic disorders these fast dissolving films are better for delivering drugs and obtaining faster therapeutic blood levels and superior in comparison to other oral conventional dosage forms.
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