脂肪肝
医学
内科学
非酒精性脂肪肝
体质指数
胰岛素抵抗
2型糖尿病
肥胖
2型糖尿病
糖尿病
代谢综合征
内分泌学
索引(排版)
逻辑回归
人口
升糖指数
超重
优势比
人口学
作者
Tracy Bonsu Osei,Anne-Marieke van Dijk,Sjoerd Dingerink,Felix P. Chilunga,Erik Beune,Karlijn Anna Catharina Meeks,Silver Bahendeka,Matthias B. Schulze,Charles Agyemang,Mary Nicolaou,Adriaan G. Holleboom,Ina Danquah
出处
期刊:Nutrients
[MDPI AG]
日期:2021-10-20
卷期号:13 (11): 3679-
摘要
The Fatty Liver Index (FLI) is a proxy for the steatotic component of non-alcoholic fatty liver disease (NAFLD). For sub-Saharan African populations, the contribution of dietary factors to the development of NAFLD in the etiology of type 2 diabetes mellitus (T2DM) remains to be clarified. We identified sex-specific dietary patterns (DPs) related to the FLI using reduced ranked regression (RRR) and evaluated the associations of these DPs with T2DM. This analysis used data from the RODAM, a multi-center cross-sectional study of Ghanaian populations living in Ghana and Europe. The daily intake frequencies of 30 food groups served as the predictor variables, while the FLI was the response variable. The odds ratios and 95% confidence intervals for T2DM were calculated per one standard deviation increase in the DP score using logistic regression. In males, the DP score explained 9.9% of the variation in their food intake and 16.0% of the variation in the FLI. This DP was characterized by high intakes of poultry, whole-grain cereals, coffee and tea, condiments, and potatoes, and the chance of T2DM was 45% higher per 1 DP score-SD (Model 2). Our results indicate that the intake of modernized foods was associated with proxies of NAFLD, possibly underlying the metabolic pathways to developing T2DM.
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